Ofloxacin Pediatric Dose Calculator

Weight-based ofloxacin dosing for children — 7.5–10 mg/kg/dose · every 12 hours · max 400 mg/dose. Enter age and weight for the dose in mg and syrup mL or tablets.

Category: AntibioticAges: ≥1 year (selected indications) – adultUpdated: 2026-09-27For: clinicians

Pediatric dosing

Enteric fever / bacterial GI infection (susceptible organisms only)

7.5–10 mg/kg/dose · every 12 hours · max 400 mg/dose
Duration: 7–14 days · 15–20 mg/kg/day. Use only when susceptibility is confirmed — fluoroquinolone resistance in S. Typhi is widespread in South Asia.

Ofloxacin dose chart by age and weight

Enteric fever / bacterial GI infection (susceptible organisms only). Weights are WHO/IAP reference medians for age — always dose on the measured weight.

AgeWeightDose (mg)Suspension 50 mg/5 mLFrequency
1 year9.3 kg69.8 mg7 mLEvery 12 hours
18 months10.6 kg79.5 mg8 mLEvery 12 hours
2 years11.8 kg88.5 mg8.9 mLEvery 12 hours
3 years14.1 kg105.8 mg10.5 mLEvery 12 hours
4 years16.2 kg121.5 mg12 mLEvery 12 hours
5 years17.5 kg131.3 mg13 mLEvery 12 hours
6 years19 kg142.5 mg14.5 mLEvery 12 hours
8 years24.4 kg183 mg18.5 mLEvery 12 hours
10 years31.1 kg233.3 mg23.5 mLEvery 12 hours
12 years39.4 kg295.5 mg29.5 mLEvery 12 hours
Computed with the PediaRx dose engine from the regimen above; caps and age limits applied.

Strengths in the calculator

  • Suspension 50 mg/5 mL (Oral)
  • Tablet 200 mg (Oral)
  • Tablet 400 mg (Oral)

Different strength on your bottle? Use “Different strength on the bottle?” under the result.

Safety

Contraindications and cautions

  • Previous fluoroquinolone tendinopathy; epilepsy; myasthenia gravis.

Pregnancy and breastfeeding

Legacy FDA category C. Avoid in pregnancy when a safer alternative exists.

Avoid if possible.

Clinical notes

Fluoroquinolone cautions as for ciprofloxacin. Many Indian products combine ofloxacin with ornidazole — check every component on the label.

Adult and adolescent (≥40 kg) dose

200–400 mg — Every 12 hours (max 400 mg per dose, 800 mg per day).

Other names and brands

  • India: Zenflox, Oflox

Brand examples only — products and strengths vary by country. Always check the label.

Frequently asked questions

What is the ofloxacin dose for children?

Enteric fever / bacterial GI infection (susceptible organisms only): 7.5–10 mg/kg/dose · every 12 hours · max 400 mg/dose. Usual duration: 7–14 days. Always use the child's measured weight and check the strength on the bottle.

How many mL of suspension 50 mg/5 mL for an 11.8 kg child?

For enteric fever / bacterial GI infection (susceptible organisms only), an 11.8 kg child (about 2 years) needs 88.5 mg per dose — 8.9 mL of Suspension 50 mg/5 mL, every 12 hours. Recalculate with the child's actual weight.

From what age can ofloxacin be given?

Age range in PediaRx: ≥1 year (selected indications) – adult. The calculator does not calculate a dose below 1 year. Each indication can have its own age and weight limits, shown with its regimen.

Is ofloxacin safe in pregnancy?

Legacy FDA category C. Avoid in pregnancy when a safer alternative exists.

Sources and editorial process

  1. Enteric fever in children — Indian Academy of Pediatrics recommendations — Indian Academy of Pediatrics
  2. Ofloxacin — prescribing information — DailyMed (U.S. National Library of Medicine)

Dosing data last updated 2026-09-27. PediaRx is built and maintained by (Medical Officer, Government of West Bengal, India — founder and developer of PediaRx). Every regimen is encoded with explicit units, maximum doses and age/weight limits and is checked by automated tests before publication. Report an error: hello@pediarx.com.

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Clinical disclaimer: reference tool for qualified health professionals. Verify every dose against current guidance and the product label before prescribing.

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