Augmentin (Amoxicillin–Clavulanate) Pediatric Dose Calculator

Weight-based amoxicillin–clavulanate dosing for children — 25 mg/kg/day in 2 divided doses. Enter age and weight for the dose in mg and syrup mL or tablets.

Category: AntibioticAges: ≥3 months and <40 kg for the paediatric mg/kg calculatorUpdated: 2026-09-27For: clinicians

Pediatric dosing

Mild/moderate infection (twice daily)

25 mg/kg/day in 2 divided doses — every 12 hours
Duration: 5–10 days
Eligibility: ≥3 months · <40 kg

Mild/moderate infection (three times daily)

20 mg/kg/day in 3 divided doses — every 8 hours
Duration: 5–10 days
Eligibility: ≥3 months · <40 kg

Severe infection / otitis media / sinusitis / LRTI (twice daily)

45 mg/kg/day in 2 divided doses — every 12 hours
Duration: 7–10 days
Eligibility: ≥3 months · <40 kg

Severe infection / otitis media / sinusitis / LRTI (three times daily)

40 mg/kg/day in 3 divided doses — every 8 hours
Duration: 7–10 days
Eligibility: ≥3 months · <40 kg

High dose — ES-600 (recurrent/persistent otitis media)

90 mg/kg/day in 2 divided doses — every 12 hours
Duration: 10 days · Only the 14:1 ES-600 product keeps clavulanate ≤6.4 mg/kg/day at this dose. 400/57 and 200/28.5 are not interchangeable with ES-600.
Eligibility: ≥3 months · <40 kg

Amoxicillin–clavulanate dose chart by age and weight

Mild/moderate infection (twice daily). Weights are WHO/IAP reference medians for age — always dose on the measured weight.

AgeWeightDose (mg)200 mg amoxicillin / 28.5 mg clavulanate per 5 mL400 mg amoxicillin / 57 mg clavulanate per 5 mLFrequency
3 months6.1 kg76.3 mg1.9 mL0.95 mLEvery 12 hours
6 months7.6 kg95 mg2.4 mL1.2 mLEvery 12 hours
9 months8.6 kg107.5 mg2.7 mL1.3 mLEvery 12 hours
1 year9.3 kg116.3 mg2.9 mL1.5 mLEvery 12 hours
18 months10.6 kg132.5 mg3.3 mL1.7 mLEvery 12 hours
2 years11.8 kg147.5 mg3.7 mL1.8 mLEvery 12 hours
3 years14.1 kg176.3 mg4.4 mL2.2 mLEvery 12 hours
4 years16.2 kg202.5 mg5.1 mL2.5 mLEvery 12 hours
5 years17.5 kg218.8 mg5.5 mL2.7 mLEvery 12 hours
6 years19 kg237.5 mg5.9 mL3 mLEvery 12 hours
8 years24.4 kg305 mg7.6 mL3.8 mLEvery 12 hours
10 years31.1 kg388.8 mg9.7 mL4.9 mLEvery 12 hours
12 years39.4 kg492.5 mg12.5 mL6.2 mLEvery 12 hours
Computed with the PediaRx dose engine from the regimen above; caps and age limits applied.

Strengths in the calculator

  • 125 mg amoxicillin / 31.25 mg clavulanate per 5 mL (Oral)
  • 200 mg amoxicillin / 28.5 mg clavulanate per 5 mL (Oral)
  • 250 mg amoxicillin / 62.5 mg clavulanate per 5 mL (Oral)
  • 400 mg amoxicillin / 57 mg clavulanate per 5 mL (Oral)
  • 600 mg amoxicillin / 42.9 mg clavulanate per 5 mL (ES-600) (Oral)
  • Tablet 625 mg (500 mg amoxicillin / 125 mg clavulanate) (Oral — do not split)
  • Tablet 1 g (875 mg amoxicillin / 125 mg clavulanate) (Oral — do not split)

Different strength on your bottle? Use “Different strength on the bottle?” under the result.

Safety

Contraindications and cautions

  • Penicillin allergy.
  • Previous cholestatic jaundice or hepatic dysfunction with amoxicillin–clavulanate.

Pregnancy and breastfeeding

Legacy FDA category B. Generally considered acceptable in pregnancy; avoid in women at risk of preterm pre-labour rupture of membranes (necrotising enterocolitis signal).

Compatible with breastfeeding.

Clinical notes

Dose on the amoxicillin component only — never on the combined strength. Check the bottle ratio (4:1, 7:1 or 14:1) against the chosen regimen. Give at the start of a meal to reduce GI upset; diarrhoea is common.

Adult and adolescent (≥40 kg) dose

500 mg every 8 hours or 875 mg every 12 hours (amoxicillin component) — Every 8 hours with food (max 875 mg per dose, 1750 mg per day).

Children ≥40 kg are dosed as adults; the paediatric mg/kg regimens are not extrapolated. Doses refer to the amoxicillin component only.

Other names and brands

Also known as Co-amoxiclav, Amoxiclav, Amox-clav, Amoxicillin + clavulanic acid, Amoxicillin clavulanate potassium.

  • India: Augmentin, Clavam, Moxclav
  • UK: Augmentin
  • USA: Augmentin

Brand examples only — products and strengths vary by country. Always check the label.

Frequently asked questions

What is the amoxicillin–clavulanate dose for children?

Mild/moderate infection (twice daily): 25 mg/kg/day in 2 divided doses. Usual duration: 5–10 days. Always use the child's measured weight and check the strength on the bottle.

How many mL of 200 mg amoxicillin / 28.5 mg clavulanate per 5 mL for an 11.8 kg child?

For mild/moderate infection (twice daily), an 11.8 kg child (about 2 years) needs 147.5 mg per dose — 3.7 mL of 200 mg amoxicillin / 28.5 mg clavulanate per 5 mL, every 12 hours. Recalculate with the child's actual weight.

From what age can amoxicillin–clavulanate be given?

Age range in PediaRx: ≥3 months and <40 kg for the paediatric mg/kg calculator. The calculator does not calculate a dose below 3 months. Each indication can have its own age and weight limits, shown with its regimen.

Is amoxicillin–clavulanate safe in pregnancy?

Legacy FDA category B. Generally considered acceptable in pregnancy; avoid in women at risk of preterm pre-labour rupture of membranes (necrotising enterocolitis signal).

Sources and editorial process

  1. Amoxicillin and clavulanate potassium for oral suspension — paediatric dosing (US prescribing information) — DailyMed (U.S. National Library of Medicine)
  2. BNF for Children — Co-amoxiclav — NICE / BMJ Group / Royal Pharmaceutical Society

Dosing data last updated 2026-09-27. PediaRx is built and maintained by (Medical Officer, Government of West Bengal, India — founder and developer of PediaRx). Every regimen is encoded with explicit units, maximum doses and age/weight limits and is checked by automated tests before publication. Report an error: hello@pediarx.com.

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Clinical disclaimer: reference tool for qualified health professionals. Verify every dose against current guidance and the product label before prescribing.

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