Ceftriaxone Pediatric Dose Calculator

Weight-based ceftriaxone dosing for children — 50–80 mg/kg/dose · once daily (IV over 30 min or IM) · max 2 g/dose. Enter age and weight for the dose in mg and injection volume.

Category: AntibioticAges: Birth – adult (hospital use)Updated: 2026-09-27For: cliniciansHospital use

Pediatric dosing

Serious bacterial infection (sepsis, pneumonia, pyelonephritis) Hospital

50–80 mg/kg/dose · once daily (IV over 30 min or IM) · max 2 g/dose
Duration: 7–14 days depending on infection · Neonates: give by IV infusion over 60 minutes. IM: ≤1 g per injection site (reconstitute with 1% lidocaine for IM only — never give lidocaine solutions IV).

Bacterial meningitis Hospital

100 mg/kg/day once daily · max 4 g/day — once daily (or 50 mg/kg every 12 hours)
Duration: 10–14 days (pathogen-dependent) · Give dexamethasone before or with the first dose where indicated.

Ceftriaxone dose chart by age and weight

Serious bacterial infection (sepsis, pneumonia, pyelonephritis). Weights are WHO/IAP reference medians for age — always dose on the measured weight.

AgeWeightDose (mg)1 g vial + 10 mL water for injection (≈100 mg/mL)Frequency
15 days3.8 kg190 mg1.9 mLOnce daily (IV over 30 min or IM)
1 month4.3 kg215 mg2.2 mLOnce daily (IV over 30 min or IM)
3 months6.1 kg305 mg3.1 mLOnce daily (IV over 30 min or IM)
6 months7.6 kg380 mg3.8 mLOnce daily (IV over 30 min or IM)
9 months8.6 kg430 mg4.3 mLOnce daily (IV over 30 min or IM)
1 year9.3 kg465 mg4.7 mLOnce daily (IV over 30 min or IM)
18 months10.6 kg530 mg5.3 mLOnce daily (IV over 30 min or IM)
2 years11.8 kg590 mg5.9 mLOnce daily (IV over 30 min or IM)
3 years14.1 kg705 mg7.1 mLOnce daily (IV over 30 min or IM)
4 years16.2 kg810 mg8.1 mLOnce daily (IV over 30 min or IM)
5 years17.5 kg875 mg8.8 mLOnce daily (IV over 30 min or IM)
6 years19 kg950 mg9.5 mLOnce daily (IV over 30 min or IM)
8 years24.4 kg1220 mg12 mLOnce daily (IV over 30 min or IM)
10 years31.1 kg1555 mg15.5 mLOnce daily (IV over 30 min or IM)
12 years39.4 kg1970 mg19.5 mLOnce daily (IV over 30 min or IM)
Computed with the PediaRx dose engine from the regimen above; caps and age limits applied.

Strengths in the calculator

  • 1 g vial + 10 mL water for injection (≈100 mg/mL) (Intravenous) — 250 mg and 500 mg vials reconstituted to the same 100 mg/mL give the same volumes.

Different strength on your bottle? Use “Different strength on the bottle?” under the result.

Safety

Contraindications and cautions

  • Neonates with hyperbilirubinaemia, especially preterm — use cefotaxime.
  • Neonates ≤28 days who need (or are expected to need) IV calcium-containing fluids — fatal precipitates reported.
  • History of anaphylaxis to penicillins or cephalosporins.

Pregnancy and breastfeeding

Legacy FDA category B. No evidence of harm; use when clearly indicated.

Compatible with breastfeeding.

Clinical notes

Never mix or co-infuse with calcium-containing solutions (e.g. Ringer's lactate) in the same line.

Adult and adolescent (≥40 kg) dose

1–2 g — Once daily IV/IM (meningitis 2 g every 12 hours) (max 2 g per dose, 4 g per day).

Other names and brands

  • India: Monocef, Oframax
  • USA: Rocephin
  • UK: Rocephin

Brand examples only — products and strengths vary by country. Always check the label.

Frequently asked questions

What is the ceftriaxone dose for children?

Serious bacterial infection (sepsis, pneumonia, pyelonephritis): 50–80 mg/kg/dose · once daily (IV over 30 min or IM) · max 2 g/dose. Usual duration: 7–14 days depending on infection. Always use the child's measured weight and check the strength on the bottle.

How many mL of 1 g vial + 10 mL water for injection (≈100 mg/mL) for an 11.8 kg child?

For serious bacterial infection (sepsis, pneumonia, pyelonephritis), an 11.8 kg child (about 2 years) needs 590 mg per dose — 5.9 mL of 1 g vial + 10 mL water for injection (≈100 mg/mL), once daily (IV over 30 min or IM). Recalculate with the child's actual weight.

From what age can ceftriaxone be given?

Age range in PediaRx: Birth – adult (hospital use). Each indication can have its own age and weight limits, shown with its regimen.

Is ceftriaxone safe in pregnancy?

Legacy FDA category B. No evidence of harm; use when clearly indicated.

Sources and editorial process

  1. BNF for Children — Ceftriaxone — NICE / BMJ Group / Royal Pharmaceutical Society
  2. Pocket Book of Hospital Care for Children, 2nd edition (2013) — World Health Organization

Dosing data last updated 2026-09-27. PediaRx is built and maintained by (Medical Officer, Government of West Bengal, India — founder and developer of PediaRx). Every regimen is encoded with explicit units, maximum doses and age/weight limits and is checked by automated tests before publication. Report an error: hello@pediarx.com.

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Clinical disclaimer: reference tool for qualified health professionals. Verify every dose against current guidance and the product label before prescribing.

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