Midazolam Pediatric Dose Calculator
Age-based midazolam dosing for children, with maximum doses, age limits and sources. Enter age and weight for the dose in mg and injection volume.
Pediatric dosing
Convulsive seizure ≥5 minutes — buccal Emergency
Convulsive seizure ≥5 minutes — intranasal Emergency
Convulsive seizure ≥5 minutes — IM (no IV access) Emergency
Midazolam dose chart by age and weight
Convulsive seizure ≥5 minutes — buccal. Weights are WHO/IAP reference medians for age — always dose on the measured weight.
| Age | Weight | Dose (mg) | Oromucosal solution 5 mg/mL (prefilled syringes 2.5 / 5 / 7.5 / 10 mg) | Injection 5 mg/mL — IM, intranasal (atomiser) or buccal | Frequency |
|---|---|---|---|---|---|
| 3 months | 6.1 kg | 2.5 mg | 0.5 mL | 0.5 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 6 months | 7.6 kg | 2.5 mg | 0.5 mL | 0.5 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 9 months | 8.6 kg | 2.5 mg | 0.5 mL | 0.5 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 1 year | 9.3 kg | 5 mg | 1 mL | 1 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 18 months | 10.6 kg | 5 mg | 1 mL | 1 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 2 years | 11.8 kg | 5 mg | 1 mL | 1 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 3 years | 14.1 kg | 5 mg | 1 mL | 1 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 4 years | 16.2 kg | 5 mg | 1 mL | 1 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 5 years | 17.5 kg | 7.5 mg | 1.5 mL | 1.5 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 6 years | 19 kg | 7.5 mg | 1.5 mL | 1.5 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 8 years | 24.4 kg | 7.5 mg | 1.5 mL | 1.5 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 10 years | 31.1 kg | 10 mg | 2 mL | 2 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
| 12 years | 39.4 kg | 10 mg | 2 mL | 2 mL | Single dose between gum and cheek; may repeat once after 10 minutes if still seizing |
Strengths in the calculator
- Oromucosal solution 5 mg/mL (prefilled syringes 2.5 / 5 / 7.5 / 10 mg) (Buccal)
- Injection 5 mg/mL — IM, intranasal (atomiser) or buccal (Intramuscular / Nasal / Buccal) — Use the 5 mg/mL strength for intranasal and IM doses (small volume).
Different strength on your bottle? Use “Different strength on the bottle?” under the result.
Safety
Contraindications and cautions
- Respiratory depression: have oxygen and a bag-valve-mask ready and monitor oxygen saturation.
Pregnancy and breastfeeding
Legacy FDA category D. Benzodiazepine: use for status epilepticus when needed — benefit outweighs risk; neonatal sedation or withdrawal if used near term.
Single doses are compatible; observe the infant for sedation.
Clinical notes
Buccal or intranasal midazolam is at least as effective as rectal diazepam and easier to give. Count every benzodiazepine dose given before arrival.
Adult and adolescent (≥40 kg) dose
10 mg — Single dose buccal, intranasal or IM; may repeat once (max 10 mg per dose).
Other names and brands
Also known as buccal midazolam, intranasal midazolam.
- India: Mezolam
- UK: Buccolam
Brand examples only — products and strengths vary by country. Always check the label.
Frequently asked questions
What is the midazolam dose for children?
Convulsive seizure ≥5 minutes — buccal: <1 year: 2.5 mg per dose · single dose between gum and cheek; may repeat once after 10 minutes if still seizing; 1 year to <5 years: 5 mg per dose · single dose between gum and cheek; may repeat once after 10 minutes if still seizing; 5 years to <10 years: 7.5 mg per dose · single dose between gum and cheek; may repeat once after 10 minutes if still seizing; ≥10 years: 10 mg per dose · single dose between gum and cheek; may repeat once after 10 minutes if still seizing. Usual duration: Acute only. Always use the child's measured weight and check the strength on the bottle.
How many mL of oromucosal solution 5 mg/mL (prefilled syringes 2.5 / 5 / 7.5 / 10 mg) for an 11.8 kg child?
For convulsive seizure ≥5 minutes — buccal, an 11.8 kg child (about 2 years) needs 5 mg per dose — 1 mL of Oromucosal solution 5 mg/mL (prefilled syringes 2.5 / 5 / 7.5 / 10 mg), single dose between gum and cheek; may repeat once after 10 minutes if still seizing. Recalculate with the child's actual weight.
From what age can midazolam be given?
Age range in PediaRx: ≥3 months. The calculator does not calculate a dose below 3 months. Each indication can have its own age and weight limits, shown with its regimen.
Is midazolam safe in pregnancy?
Legacy FDA category D. Benzodiazepine: use for status epilepticus when needed — benefit outweighs risk; neonatal sedation or withdrawal if used near term.
Sources and editorial process
- BNF for Children — Midazolam — NICE / BMJ Group / Royal Pharmaceutical Society
- Buccolam oromucosal solution — Summary of Product Characteristics — electronic medicines compendium (UK)
- Evidence-based guideline: treatment of convulsive status epilepticus in children and adults (Glauser et al., Epilepsy Currents 2016) — American Epilepsy Society
Dosing data last updated 2026-09-28. PediaRx is built and maintained by Dr. Shounak Pal, MBBS (Medical Officer, Government of West Bengal, India — founder and developer of PediaRx). Every regimen is encoded with explicit units, maximum doses and age/weight limits and is checked by automated tests before publication. Report an error: hello@pediarx.com.
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Clinical disclaimer: reference tool for qualified health professionals. Verify every dose against current guidance and the product label before prescribing.
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