Simethicone (simeticone) Pediatric Dose Calculator

Age-based simethicone dosing for children, with maximum doses, age limits and sources. Enter age and weight for the dose in mg and drops mL.

Category: Gastro / AGEAges: Birth – adultUpdated: 2026-09-27For: clinicians

Pediatric dosing

Wind / gas discomfort (supportive)

<2 years: 20 mg per dose · after feeds, up to three times daily · max 240 mg/day
Duration: As needed
≥2 years: 40 mg per dose · after meals, up to three times daily · max 480 mg/day
Duration: As needed

Simethicone (simeticone) dose chart by age and weight

Wind / gas discomfort (supportive). Weights are WHO/IAP reference medians for age — always dose on the measured weight.

AgeWeightDose (mg)Drops 40 mg/mLDrops 66.7 mg/mL (20 mg per 0.3 mL)Frequency
15 days3.8 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
1 month4.3 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
3 months6.1 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
6 months7.6 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
9 months8.6 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
1 year9.3 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
18 months10.6 kg20 mg0.5 mL0.3 mLAfter feeds, up to three times daily
2 years11.8 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
3 years14.1 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
4 years16.2 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
5 years17.5 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
6 years19 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
8 years24.4 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
10 years31.1 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
12 years39.4 kg40 mg1 mL0.6 mLAfter meals, up to three times daily
Computed with the PediaRx dose engine from the regimen above; caps and age limits applied.

Strengths in the calculator

  • Drops 40 mg/mL (Oral)
  • Drops 66.7 mg/mL (20 mg per 0.3 mL) (Oral)

Different strength on your bottle? Use “Different strength on the bottle?” under the result.

Safety

Pregnancy and breastfeeding

Legacy FDA category A. Not absorbed; considered safe.

Not absorbed; compatible with breastfeeding.

Clinical notes

Evidence for infant colic is weak; reassurance and feeding advice come first. Safer than dicyclomine in young infants.

Adult and adolescent (≥40 kg) dose

40–125 mg — After meals and at bedtime (max 125 mg per dose, 500 mg per day).

Other names and brands

Also known as Simeticone, Activated dimeticone.

  • USA: Mylicon
  • UK: Infacol

Brand examples only — products and strengths vary by country. Always check the label.

Frequently asked questions

What is the simethicone dose for children?

Wind / gas discomfort (supportive): <2 years: 20 mg per dose · after feeds, up to three times daily · max 240 mg/day; ≥2 years: 40 mg per dose · after meals, up to three times daily · max 480 mg/day. Usual duration: As needed. Always use the child's measured weight and check the strength on the bottle.

How many mL of drops 40 mg/mL for an 11.8 kg child?

For wind / gas discomfort (supportive), an 11.8 kg child (about 2 years) needs 40 mg per dose — 1 mL of Drops 40 mg/mL, after meals, up to three times daily. Recalculate with the child's actual weight.

From what age can simethicone be given?

Age range in PediaRx: Birth – adult. Each indication can have its own age and weight limits, shown with its regimen.

Is simethicone safe in pregnancy?

Legacy FDA category A. Not absorbed; considered safe.

Sources and editorial process

  1. Simethicone infant drops — OTC labelling — DailyMed (U.S. National Library of Medicine)

Dosing data last updated 2026-09-27. PediaRx is built and maintained by (Medical Officer, Government of West Bengal, India — founder and developer of PediaRx). Every regimen is encoded with explicit units, maximum doses and age/weight limits and is checked by automated tests before publication. Report an error: hello@pediarx.com.

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Clinical disclaimer: reference tool for qualified health professionals. Verify every dose against current guidance and the product label before prescribing.

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